基本信息
姓名:邱健 性别:男 政治面貌:中共党员
邮箱: qiujian@sklmg.edu.cn
职称:教授
联系电话:0731-89752073
地址: 湖南省长沙市开福区湘雅路87号
教育经历
工作经历
2019-至今 威尼斯84881 教授
2014-2019 瑞士洛桑联邦理工大学 博士后
2013-2014 德国福莱堡大学 博士后
社会兼职
湖南省遗传学会理事 (2019-至今)
湖南省罕见病专业委员会理事 (2019-至今)
项目经费
2023-2025 威尼斯84881前沿交叉项目(主持)
2023-2026 国自然面上项目(主持)
2021-2023 湖南省杰出青年基金(主持)
2020-2023 国自然面上项目(主持)
2020-2022 湖湘高层次人才聚集工程创新团队(主持)
2019-2021 国家“海外高层次人才计划”青年项目(主持)
2015-2017 EMBO Long-Term Fellowship(主持)
研究方向
线粒体生物生成和功能调控
代表性论文
1、 Qiu, J.*, Wenz, L.S.*, Zerbes, R.M., Oeljeklaus, S., Bohnert, M., Stroud, D.A., Wirth, C., Ellenrieder, L., Thornton, N., Kutik, S., Wiese, S., Schulze-Specking, A., Zufall, N., Chacinska, A., Guiard, B., Hunte, C., Warscheid, B., van der Laan, M., Pfanner, N., Wiedemann, N., and Becker, T. (2013). Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell 154(3):596-608. doi: 10.1016/j.cell.2013.06.033.
2、 Shiota, T., Imai, K., Qiu, J., Hewitt, V.L., Tan, K., Shen, H.H., Sakiyama, N., Fukasawa, Y., Hayat, S., Kamiya, M., Elofsson, A., Tomii, K., Horton, P., Wiedemann, N., Pfanner, N., Lithgow, T. and Endo, T. (2015). Molecular architecture of the active mitochondrial protein gate. Science. 349(6255):1544-8. doi: 10.1126/science.aac6428.
3、 Höhr, A., Lindau, C., Wirth, C., Qiu, J., Stroud, D., Kutik, S., Guiard, B., Hunte, C., Becker, T., Pfanner, N., Wiedemann, N. (2018). Membrane protein insertion through a mitochondrial beta-barrel gate. Science. 359(6373):eaah6834. doi: 10.1126/science.aah6834.
4、 Araiso, Y., Tsutsumi, A., Qiu, J., Imai, K., Shiota, T., Song, J., Lindau, C., Wenz, L.S., Sakaue, H., Yunoki, K., Kawano, S., Suzuki, J., Wischnewski, M., Schütze, C., Ariyama, H., Ando, T., Becker, T., Lithgow, T., Wiedemann, N., Pfanner, N., Kikkawa, M., Endo, T. (2019). Structure of mitochondrial import gate reveals distinct preprotein paths. Nature. 575(7782):395-401. doi: 10.1038/s41586-019-1680-7.
5、Takeda, H., Tsutsumi, A., Nishizawa, T., Lindau, C., Busto, J.V., Wenz, L.S., Ellenrieder, L., Imai, K., Straub, S.P., Mossmann, W., Qiu, J., Yamamori, Y., Tomii, K., Suzuki, J., Murata, T., Ogasawara, S., Nureki, O., Becker, T., Pfanner, N., Wiedemann, N., Kikkawa, M., Endo, T. (2021). Mitochondrial sorting and assembly machinery operates by β-barrel switching. Nature. 590(7844):163-169. doi: 10.1038/s41586-020-03113-7.
6、Huang, K., Wang, D.D., Hu, W.B., Zeng, W.Q., Xu, X., Li Q.X., Bi, F.F., Yang, H., Qiu, J.# (2022). Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSALR mouse models. J. Transl. Med. 20(1):588. doi: 10.1186/s12967-022-03806-9.
7、Qu Y.Q.*, Zhai R.N.*, Wang D.D., Wang Z., Hou G.J., Wu C.C., Tang M.A., Xiao X.B., Jiao J., Ba Y., Zhou F., Qiu J.#, Yao W.# (2023). Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis. J. Transl. Med. 21(1):365. doi: 10.1186/s12967-023-04241-0.
* Equal contribution
# Correspondence